DE - take a look at your browser keyboard shortcuts - the ones that affect page. The focus is probably going out of the page area first - going to the browser(ie menu/bookmark/status/edge) control area. Then there are several possibilities as to which 'browser command' is taking over and erasing our work (forward,backward,page refresh, etc.).
The combo keys mostly involve the Fx keys, control combos, and a few shift-key commands - so it MAY not be a single key sequence cause- it may be two or three causes.
NOTE: There are times when the Chrome based browser simply gets hosed and the ctrl key is turned on, turned off, or even re-mapped. I have seen this in the browser/window/tab remapping one 'shortcut key' to another shortcut altogether. Example: Page-zoom+/- getting remapped to 'next tab', 'tab in page to different field', 'new tab' or even 'new window'.
So - to the list of possibilities add in browser program error (possibly from memory overflow or memory mapping program error).
The 'backspace key' is ONLY going to 'erase' our work if the 'cursor focus' is first shifted from the 'text area' to the 'page menu' area. And, yes, that will duplicate the problem we experience. I have verified that. The problem is How is the focus getting shifted - I am having to do that manually with the cursor - haven't gotten an 'accidental key sequence' to do it yet.