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This is fascinating. 

By: Decomposed in 6TH POPE | Recommend this post (2)
Thu, 26 Aug 21 12:44 PM | 31 view(s)
Boardmark this board | 6th Edition Pope Board 		Msg. 22640 of 60008
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This is fascinating. Marek's disease is a chicken disease. Its discussion therefore hasn't become political. Consequently, you can actually find truthful information on Wikipedia about the effect "leaky" vaccines have had on that virus. It's not good. Marek's disease has gone from rarely fatal to 100% fatal in unvaccinated birds.

Normally, viruses do not mutate to become deadlier. Killing the hosts prevents their spread which is contrary to the only goal viruses have: spreading. But thanks to vaccines that protect the vaccinated, deadlier variants can appear and thrive.

This sheds new light on "our" [collective] decision to not get vaccinated. The decision warrants a re-think. Even if not getting vaccinated was, at the pandemic's outset, the right move for individuals and society, what's done is done. The vaccines are widely used and may in time do to SARS-CoV-2 what they did to Marek. Given that there must by now be millions of SARS-CoV-2 variants extant, I'd say the likelihood of that is great.

While my position had been that I'd get the Novavax shot "when I have to" - meaning, when I want to go on a cruise or attend my son's graduation or something like that - it is evolving toward an almost certainty in the not too distant future. Viruses don't really care if we are intelligent or educated about how they work. They'll happily kill the smart right along with the dumb if doing so doesn't interfere with their only goal. I suggest you mull that over before digging in your heels and insisting you'll never get the shot.

Here's an excerpt from the Wikipedia article:

Because vaccination does not prevent infection with the virus, Marek's is still transmissible from vaccinated flocks to other birds, including the wild bird population. The first Marek's disease vaccine was introduced in 1970. The disease would cause mild paralysis, with the only identifiable lesions being in neural tissue. Mortality of chickens infected with Marek's disease was quite low. Current strains of Marek virus, decades after the first vaccine was introduced, cause lymphoma formation throughout the chicken's body and mortality rates have reached 100% in unvaccinated chickens. The Marek's disease vaccine is a "leaky vaccine", which means that only the symptoms of the disease are prevented. Infection of the host and the transmission of the virus are not inhibited by the vaccine. This contrasts with most other vaccines, where infection of the host is prevented. Under normal conditions, highly virulent strains of the virus are not selected. A highly virulent strain would kill the host before the virus would have an opportunity to transmit to other potential hosts and replicate. Thus, less virulent strains are selected. These strains are virulent enough to induce symptoms but not enough to kill the host, allowing further transmission. However, the leaky vaccine changes this evolutionary pressure and permits the evolution of highly virulent strains. The vaccine's inability to prevent infection and transmission allows the spread of highly virulent strains among vaccinated chickens. The fitness of the more virulent strains is increased by the vaccine.

http://en.wikipedia.org/wiki/Marek%27s_disease




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