I confess I haven't read this very carefully. And I am weak in statistics. This could have many factors, and probably does. Fentanyl; Covid; mRNA; depression; etc.
http://www.zerohedge.com/medical/annual-us-excess-deaths-relative-other-developed-countries-are-growing-alarming-rate
"In 2021, more than 892,000 of the 3,456,000 deaths the U.S. experienced, or about 1 in 4, were “excess deaths.” In 2019, that number was 483,000 deaths, or nearly 1 in 6. That represents an 84.9% increase in excess deaths in the U.S. between 2019 and 2021.
Excess deaths refer to the actual number of deaths that occur in a given year compared with expected deaths over that same time period based on prior years or, as in this study, in other countries."