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Scientists create ‘woolly mouse’ on the way to recreating the woolly mammoth

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March 13, 2025

Scientists create ‘woolly mouse’ on the way to recreating the woolly mammoth

by Hans Bader
LibertyUnyielding.com


“Biotech startup Colossal Biosciences is working to bring back the woolly mammoth, the dodo bird, and the Tasmanian tiger. On the way to achieving these goals, the company has created an entirely new strain: the woolly mouse,” reports The Doomslayer.

Ben Lamm, Colossal’s CEO, said his research “team had been studying ancient mammoth genomes and comparing them with those of Asian elephants to understand how they differ and had already begun genome-editing cells of the latter. Now the team say they have fresh support for their approach after creating healthy, genetically modified mice that have traits geared towards cold tolerance, including woolly hair,” reports The Guardian. The team modified mouse “genes associated with various hair-related traits similar to those found in mammoths.”

As The Guardian explains,

the team used a number of genome editing techniques to either genetically modify fertilized mouse eggs or modify embryonic mouse stem cells and inject them into mouse embryos, before implanting them into surrogates.

The team focused on disrupting nine genes associated with hair color, texture, length or pattern or hair follicles. Most of these genes were selected because they were already known to influence the coats of mice, with the induced disruptions expected to produce physical traits similar to those seen in mammoths, such as golden hair.

However, two of the genes targeted in the mice were also found in mammoths, where they are thought to have contributed to a woolly coat, with the changes introduced by the researchers designed to make the mouse genes more mammoth-like.

The team also disrupted a gene associated with the way fats are metabolized in mice and was also found in mammoths, which they suggest could play a role in cold adaptation.


Genetic engineering recently produced pork and bacon that people who are allergic to pork can eat.

A genetically-modified chicken lays eggs that people allergic to eggs can eat. Scientists have genetically engineered a cow that produces human insulin in its milk.

Scientists have engineered a virus to steal proteins from the HIV virus, in hopes of eliminating AIDS.

A virus is being used to cure deafness in new gene therapy. Researchers also discovered that a plant virus could be used to save crops from root-eating pests.

http://libertyunyielding.com/2025/03/13/scientists-create-woolly-mouse-on-the-way-to-recreating-the-woolly-mammoth/

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